OK, there have been some posts trying to find out what comic the characters from the cover of the Prism Comics GLBT Guide come from. The answer is: None.
The cover was the creation of artist Joe Phillips, who created the cover specifically for the guide. If you go to his Web site you’ll certainly recognize his artwork from Xodus, XY and some Bud Light ads. You can also get some very cool wallpapers for your desktop from his site, just make sure to follow the rules.
There you have it, the artist is Joe Phillips and sadly the comic doesn’t exist – bummer.
Thanks Zan for finally clearing this up