Earlier this week, gamers started complaining about a game-ending glitch in Fable II: at the start of the Monks Quest mission, if a player skipped a conversation and cut scene with an abbot and then left the area, the game wouldn't allow the player to progress any further. That's a pretty big penalty for being impatient. Obviously not something Lionhead intended, one of the game's developers, "Ted," announced that they are working to resolve this issue.
We are aware that a minority of people playing Fable II over the last few days have encountered an issue where the Abbot becomes unresponsive at the beginning of Monks Quest in Oakfield. This is an isolated issue, but we are currently looking into it as a matter of priority. If you have already encountered this issue, there is unfortunately no work-around at this time, but we will keep you updated on any progress made.
For now, if you're playing the game, their only advice is to make sure you listen to the abbot's instructions all the way once you start the quest, and don't leave the area. If you've already fallen victim to the glitch, as he says above, there's not much you can do at that point.