One of the early names to come up when an adaptation of Uncharted was first being bandied about Hollywood was writer/director David O. Russell. Now, according to The Hollywood Reporter, Russell is back in the mix, and has reportedly signed a deal to write and direct the film. He had been most recently attached to an adaptation of the novel Pride and Prejudice and Zombies, but with that movie losing its leading lady Natalie Portman, it seems like Russell may have moved onto something that was a bit more of a sure thing at this point.
Russell is possibly best known for quirky indie dramas like Spanking the Monkey and I Heart Huckabees (and for making Lily Tomlin freak the eff out). However he also directed the (really pretty good) Iraq war adventure-comedy Three Kings, which is probably closest in feel to the Uncharted series.
Unlike some video games that have gotten the big screen treatment, Uncharted could actually turn out decent, probably because the game hews so close to classical Hollywood cinema already. Any ideas you'd like to see them follow up on, any cast you'd like to recommend? Personally I'd like to see Emily Rose, the voice of Elena in the games, take on the actual role in the film: she's doing pretty good work on SyFy's Haven, and I know I'd have a hard time hearing someone else in the role. Although really, as long as they don't cast one of the Jonas brothers as Nathan or anyone from the Twilight films, I'll probably be fine.